Crystallics was founded in the year 2000 and is a science driven contract research organization (CRO) specialized in identification, characterization and selection of the physical forms of drug substances, as well as preformulation and formulation services for the pharmaceutical industry.
Crystallics was a pioneer in the field of solid state and under the name of Avantium Pharma (see History) developed a number of unique and proprietary technologies. These technologies include the vertical transmission X-ray powder diffraction technology with multiwell plate analysis and the proprietary ‘shaking’ method of the well plate (x,y movement) which enables a much faster analysis of the samples. Crystallics is currently the only CRO which holds a license from the inventor to use these technologies.
These unique, proprietary technologies, together with a strong customer focus, make Crystallics a leader in solid form screening and selection, preformulation and formulation design. Over the last 15 years, the vast majority of large and medium size pharmaceutical companies, as well as, many smaller biotechnology companies have commissioned work with Crystallics.
Crystallics focuses on the following keys to success:
o Tailored, science based approach to meet the needs of the customer and their compound
o Comprehensive solid state chemistry support from lead optimization to late stage development and product life-cycle management
o Flexibility in screen size, experimental set-up, reporting and business model
o Diversity through rational experimental design, solvent & counter-ions selection, crystallization modes and conditions and characterization techniques
o Proprietary technology & know-how enhancing productivity and ultimately speed to market
o Uniquely integrated crystallization workflow, patented well plate technology, proprietary XRPD set-up, and other proprietary techniques
o In-house developed informatics including Experimental Design Software (Aspect) and eReporting
o Smart intellectual property insights and advice
o Experienced & knowledge team of scientists
o >800 projects over more than 15 years
o High proportion of repeat business
o Project leaders with PhDs in crystallography and organic synthetic chemistry