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Crystal structure by X-ray |
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X-ray crystal structure from single crystal and powder
Knowledge of the crystal structure at atomic level and intermolecular interactions offer a wealth of information crucial for absolute configuration (enantiomers), phase identification, quality control, process development and patent protection. X-ray Diffraction is widely recognized as the most reliable tool for the crystal structure analysis of pharmaceutical solids and crystal form identification.
Availability of a single crystal of the drug substance is preferred due to the speed and accuracy of the structure determination. However, it is not always possible to obtain a crystal of suitable size for data collection. In those cases we can solve the crystal structure from X-ray powder diffraction data. We also offer X-ray powder diffraction measurements at ambient conditions and/or at variable temperature or humidity.
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